Author

William N. D. Gao

Harvard UniversityORCID 0000-0002-9415-331XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:statistical model· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

Dongming LiangiD· 2 shared Elena RivasiD· 2 shared Hao WuiD· 2 shared Carlos J. Gallardo-DoddiD· 1 shared Claudia KutteriD· 1 shared Emily R. FeiermaniD· 1 shared Erica KorbiD· 1 shared Fan LiiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersGenomics

Dongming LiangORCID

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Author profile →

5 papers

Recent·Most cited

Spatial mapping of RNA turnover kinetics and regulatory landscapes of mRNA stability in the mammalian brain

Qi Qiu, Hongjie Zhang, Zijie Xia, William N. D. Gao, Julie Leu, Dongming Liang, Ying Li, Yijing Su, Emily R. Feierman, Van Horn, Guo‐li Ming, Erica Korb, Hongjun Song, Zhaolan Zhou, Hao Wu

The paper introduces spatial NT-seq to map RNA turnover and stability in the mouse brain, revealing spatial heterogeneity and kinetics scaling mechanisms in response to ECS.

bioRxiv · Jan 29, 2026 · PreprintGenomics

Highly sensitive and scalable time-resolved RNA sequencing in single cells with scNT-seq2

Qi Qiu, Hongjie Zhang, William N. D. Gao, Fan Li, Dongming Liang, Hao Wu

scNT-seq2 improves time-resolved single-cell RNA sequencing by enhancing sensitivity and scalability for studying transcriptional dynamics.

bioRxiv · Jun 3, 2025 · PreprintGenomics

RNAhub - an automated pipeline to search and align RNA homologs with secondary structure assessment

Marcin Magnus, William N. D. Gao, Nivedita Dutta, Quentin Vicens, Elena Rivas

RNAhub generates RNA multiple sequence alignments and assesses conserved RNA structure using covariation analysis.

Nucleic Acids Research · Apr 17, 2025Peer-reviewedBioinformatics

Analysis at single-cell resolution identifies a stable mammalian tRNA-mRNA interface and increased translation efficiency in neurons

William N. D. Gao, Carlos J. Gallardo-Dodd, Claudia Kutter

The paper analyzes single-cell data to show stable codon and anticodon usage across cell types, with neurons having higher translation efficiency due to increased tRNAAla (AGC) anticodons.

Genome Research · Jan 1, 2022Peer-reviewedGenomics

Discovery of 17 conserved structural RNAs in fungi

William N. D. Gao, Thomas A Jones, Elena Rivas

The paper identifies 17 structurally conserved non-coding RNAs in fungal genomes using a bioinformatics method combining homology search and covariation analysis.

Nucleic Acids Research · Apr 22, 2021Peer-reviewedBioinformatics