Takaaki Kato

CLOSING THE CONFORMATIONAL CYCLE OF THE BETA-BARREL ASSEMBLY MACHINERY

This study determines cryo-EM structures of the E. coli BAM complex in different environments, identifying new conformational states involved in lateral-gate closure during OMP insertion.

CAMSAP2 condensates drive a γ-TuRC-independent pathway for non-centrosomal microtubule nucleation

This study identifies CAMSAP2 condensates as a γ-TuRC-independent mechanism for non-centrosomal microtubule nucleation through phase separation and tubulin organization.

Human spastin functions as an ATPase-independent microtubule nucleator via ring-stack formation

This study shows human spastin functions as an ATPase-independent microtubule nucleator by forming ring-stack structures, redefining its role in microtubule dynamics and HSP pathology.