Markus Kalkum

De Novo Hepatic Pyrimidine Synthesis Regulates Systemic Energy Homeostasis

This study shows that reduced hepatic pyrimidine synthesis during fasting and obesity promotes insulin resistance and obesity by increasing hepatic glucose production and decreasing insulin clearance.

Proinflammatory circulating extracellular vesicles from type 1 diabetes patients contribute to beta cell cytotoxicity and disease pathogenicity

The reticulocyte restriction: invasion ligand RBP1a of Plasmodium vivax targets human TfR1, prohibitin-2, and basigin

This paper identifies new receptors for Plasmodium vivax invasion, including prohibitin-2, using erythroid cell lines as reticulocyte surrogates and proximity labeling.