James D. Wasmuth

mimicDetector identifies protein mimicry between pathogens and hosts by improving sensitivity and specificity in short-sequence alignment.

This study identifies structural variants in wild Caenorhabditis elegans populations using long-read sequencing, revealing their role in phenotypic diversity and adaptation.

The paper sequences and analyzes the genome of Myxobolus sp., a myxozoan parasite, revealing its large size, high repetitiveness, and gene family expansions, suggesting functional roles in host interaction.

This study shows that the nematode Heligmosomoides bakeri can opportunistically feed on blood, leading to increased collagen gene expression and growth advantage, suggesting broader blood-feeding behavior in nematodes.

This paper constructs a single-cell transcriptomics atlas for the parasitic nematode Heligmosomoides bakeri using orthologs from C. elegans to compare cell types and biological processes.

The paper examines how genome assembly choices impact gene discovery in three nematode species, showing significant variation in gene family composition across different assemblers.

This study evaluates how FASTQ read order affects structural variation calling in long-read sequencing data using PacBio data from C. elegans isolates.

The paper identifies molecular mimicry in Plasmodium falciparum proteins by comparing their tertiary structures to human proteins, finding 393 potential mimics with 51 supported by additional data.

The paper benchmarks structural variant prediction tools in C. elegans, showing performance varies by variant type and sequencing depth, and highlights the need for real-data reference datasets.

This paper generates RNA-seq data from Heligmosomoides bakeri across its parasitic life stages, identifying sexual dimorphism, stress responses, and developmental gene expression patterns.

This study identifies genomic signatures of benzimidazole drug resistance in Haemonchus contortus using field populations with defined treatment histories, showing the isotype-1 β-tubulin gene as the primary resistance locus.

The paper uses Nanopore sequencing to generate high-quality genomes and identify structural variants in Giardia isolates, revealing heterozygosity and variant-specific surface proteins.

The paper identifies a horizontal transfer of a nematode retrotransposon to a shrew host and presents a method to distinguish contamination from horizontal transfer.

This study compares two genomes of Haemonchus contortus to identify technical errors and biological differences, finding significant assembly and annotation discrepancies.