Elizabeth Redman

The development and validation of long-read ITS-1/5.8S/ITS-2 nemabiome metabarcoding using Oxford Nanopore Technologies (ONT) sequencing for ovine gastrointestinal nematodes and the design of primers suitable for its direct application to fecal DNA.

Naturally occurring variation in a cytochrome P450 modifies thiabendazole responses independent of beta-tubulin

This paper identifies a cytochrome P450 gene variant that contributes to benzimidazole resistance in nematodes, independent of beta-tubulin mutations.

Molecular evidence of widespread benzimidazole drug resistance in Ancylostoma caninum from domestic dogs throughout the USA and discovery of a novel isotype-1 β-tubulin benzimidazole resistance mutation.

This paper identifies widespread benzimidazole resistance in Ancylostoma caninum from dogs across the USA, including a novel β-tubulin mutation and confirms its functional significance.

Genomic signatures of selection associated with benzimidazole drug treatments in Haemonchus contortus field populations

This study identifies genomic signatures of benzimidazole drug resistance in Haemonchus contortus using field populations with defined treatment histories, showing the isotype-1 β-tubulin gene as the primary resistance locus.

Multiple drug resistance in hookworms infecting greyhound dogs in the USA

This study identifies high prevalence and intensity of multiple-drug-resistant Ancylostoma caninum in greyhound dogs in the USA, with strong genetic and phenotypic evidence of resistance.

Extensive genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm

The paper presents a high-quality, chromosome-scale genome assembly of Haemonchus contortus using long-read sequencing, revealing genetic diversity and transcriptional regulation.

A database for ITS2 sequences from nematodes

The paper presents a database of ITS2 sequences from nematodes and the software used to build it, along with tools to create ITS2 databases for other taxonomies.

Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus

The paper identifies a single major QTL on chromosome V associated with ivermectin resistance in Haemonchus contortus through genome-wide analysis of genetic crosses.