Genomic signatures of selection associated with benzimidazole drug treatments in Haemonchus contortus field populations
Janneke Wit, Matthew L. Workentine, Elizabeth Redman, Roz Laing, Lewis Stevens, James Anthony Cotton, Umer Naveed Chaudhry, Qasim Ali, Erik C. Andersen, Sam Yeaman, James D. Wasmuth, John S. Gilleard
This study identifies genomic signatures of benzimidazole drug resistance in Haemonchus contortus using field populations with defined treatment histories, showing the isotype-1 β-tubulin gene as the primary resistance locus.
International Journal for Parasitology · Sep 1, 2022Peer-reviewedGenomics