Author
Harvard UniversityORCID 0000-0002-9542-2913Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Helena Casademunt, Hongruo Zhang, John Laver, Core Francisco Park, Sophia Kim, William Fredenberg, Wesley Hung, John Calarco, Mei Zhen, Aravinthan D.T. Samuel
The paper analyzes brain-wide neural activity in C. elegans during olfactory navigation and identifies functional circuits linking sensory input to motor behavior across different environments and behavioral states.
bioRxiv · Nov 3, 2026 · PreprintNeuroscience
Jose David Aguirre Aguilera, Xuan Wan, Carsten H. Tischbirek, Nicholas Markarian, Core Francisco Park, Long Cai, Paul W. Sternberg
This paper develops a single-molecule fluorescence in situ hybridization workflow for whole-organism spatial transcriptomics in C. elegans, enabling single-cell resolution and multiplex gene profiling.
bioRxiv · Apr 11, 2026 · PreprintNeuroscience
Xuan Wan, Tingtao Zhou, Vladislav Susoy, Alessandro Groaz, Core Francisco Park, John F. Brady, Aravinthan D. T. Samuel, Paul W. Sternberg
This paper shows that C. elegans males use an antagonistic sensory system to navigate pheromone gradients, with head and tail neurons having opposing roles in movement control.
Nature Communications · Feb 13, 2026Peer-reviewedNeuroscience
Yaron Meirovitch, Ishaan Singh Chandok, Core Francisco Park, Pavel Potocek, Lu Mi, Shashata Sawmya, Yicong Li, Thomas L. Athey, Vladislav Susoy, Neha Karlupia, Yuelong Wu, Daniel Raimund Berger, Richard Lee Schalek, Caitlyn A. Bishop, Daniel Xenes, , Nir Shavit
SmartEM accelerates electron microscopy image acquisition by using machine learning to intelligently allocate imaging time, achieving up to 7-fold speedup in connectomic samples.
Nature Methods · Dec 29, 2025Peer-reviewedNeuroscience
Yicong Li, Core Francisco Park, Daniel Xenes, Caitlyn A. Bishop, Daniel Raimund Berger, Aravinthan D. T. Samuel, Brock A. Wester, Jeff William Lichtman, Hanspeter Pfister, Wanhua Li, Yaron Meirovitch
EM-Compressor uses Variational Autoencoders to compress EM images for connectomics, reducing data size to 1/128th while preserving features needed for segmentation.
Lecture notes in computer science · Jan 1, 2025Peer-reviewedNeuroscience
Elisa Catherine Pavarino, Emma Yang, Nagaraju Dhanyasi, Mona D. Wang, Flavie Bidel, Xiaotang Lu, Fuming Yang, Core Francisco Park, Mukesh Bangalore Renuka, Brandon D. Drescher, Aravinthan D. T. Samuel, Binyamin Hochner, Paul S. Katz, Mei Zhen, Jeff William Lichtman, Yaron Meirovitch
mEMbrain provides an interactive MATLAB tool for connectomic segmentation, enabling user-friendly analysis of EM datasets with pre-trained networks and ground truth annotations.
Frontiers in Neural Circuits · Jun 15, 2023Peer-reviewedNeuroscience
Core Francisco Park, Mahsa Barzegar-Keshteli, Kseniia A. Korchagina, Ariane Delrocq, Vladislav Susoy, Corinne L. Jones, Aravinthan D. T. Samuel, Sahand Jamal Rahi
The paper develops a deep learning method with targeted augmentation to track neurons in moving C. elegans, reducing manual annotation needs and enabling analysis of neuronal behavior.
bioRxiv · Mar 15, 2022 · PreprintNeuroscience
Vladislav Susoy, Wesley Hung, Daniel K. Witvliet, Joshua E. Whitener, Min Wu, Core Francisco Park, Brett J. Graham, Mei Zhen, Vivek Venkatachalam, Aravinthan D. T. Samuel
The paper studies brain-wide activity in C. elegans during mating, showing how sensory context shapes diverse neural dynamics across different behavioral components.
Cell · Sep 1, 2021Peer-reviewedNeuroscience