Wesley Hung

The paper analyzes brain-wide neural activity in C. elegans during olfactory navigation and identifies functional circuits linking sensory input to motor behavior across different environments and behavioral states.

The paper identifies three muscle-specific DAF-16/FOXO targets activated by reduced insulin/IGF-1 signaling in C. elegans through transcriptomic and chromatin analyses.

This study shows that UBR-1 deficiency in C. elegans causes ivermectin resistance by disrupting glutamate signaling and GluCl function.

This study identifies a master neuron in C. elegans that modulates forward and backward movement through tonic and phasic activity at different timescales.

The paper shows that UBR-1 regulates synaptic strength between GABAergic and glutamatergic signaling in C. elegans by suppressing inhibitory glutamate signaling in DVB neurons.

The paper studies how C. elegans chemosensory neurons encode olfactory information through ensemble activity and natural stimuli.

The paper shows that juvenile C. elegans generate symmetric motor patterns through an asymmetric motor circuit, with dorsal bending driven by synaptic wiring and ventral bending via extrasynaptic signaling from premotor interneurons.

This study identifies TWK-40, a K2P channel, as essential for regulating rhythmic motor activity in C. elegans by modulating DVB neuron function and Ca2+ oscillations.

The paper identifies cholecystokinin signaling as essential for robust escape steering in C. elegans by modulating motor neuron activity during escape responses.

The paper studies brain-wide activity in C. elegans during mating, showing how sensory context shapes diverse neural dynamics across different behavioral components.

This study shows that corollary discharge from the motor circuit to the sensory processing circuit in C. elegans sustains motor state during thermotactic navigation.

The paper shows that UBR-1 in C. elegans regulates glutamate levels, affecting motor neuron activity and locomotion.

The paper identifies class A motor neurons in C. elegans as intrinsic oscillators driving reverse locomotion without premotor interneurons.

The paper identifies a neuroendocrine neuron, RID, in C. elegans that sustains forward movement through the neuropeptide FLP-14.