Author
Research Institute of Molecular PathologyORCID 0000-0002-9556-5914Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Matthias Hinterndorfer, Caroline Schätz, S. Schmitt…·Georg E. Winter
This study shows that SERDs induce ER SUMOylation, which recruits co-repressors to suppress transcription, rather than relying on ER degradation for their activity.
Jianfeng Ge, Shoko Hirosue, Leticia Castillon…·Sakari Vanharanta
This study identifies HIF1A as a key inhibitor of VHL null cell fitness and shows that combined VHL/HIF1A inactivation can confer resistance to PROTAC-based therapies.
Veveeyan Suresh, Christoph Hafemeister, Andri Konstantinou…·Valerie Fock
This study models EWS::FLI1 fluctuations in Ewing sarcoma, showing that partial depletion promotes metastasis and identifies gene clusters and transcription factors linked to poor prognosis.