Author

Xiang Yu Zheng

Albert Einstein College of MedicineORCID 0000-0001-8656-6598Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:batch correction / integration· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Deyou ZhengiD· 4 shared Alexander FerrenaiD· 2 shared Bang H. HoangiD· 2 shared Artem LomakiniD· 1 shared Barlas GökeriD· 1 shared Bernice E. MorrowiD· 1 shared Christina N. CurtisiD· 1 shared David Entenberg· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersCancer Biology

Deyou ZhengORCID

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4 papers

Recent·Most cited

Enforced ZFP281 expression delays breast cancer initiation and can provide lifelong protection against breast cancer metastasis

Deepak Kumar Singh, Hongwei Zhou, Nyima Sherpa, Xiang Yu Zheng, Artem Lomakin, Pedram Razghandi, Xin Hunag, Rama Kadamb, Suryansh Shukla, Luis E. Valencia Salazar, David Entenberg, Deyou Zheng, Christina N. Curtis, Jianlong Wang, Julio A. Aguirre‐Ghiso

This study shows that ZFP281 expression delays breast cancer initiation and prevents metastasis by enforcing a dormant state in cancer cells.

bioRxiv · Apr 15, 2026 · PreprintCancer Biology

Comprehensive single cell transcriptomics analysis of murine osteosarcoma uncovers Skp2 function in metastasis, genomic instability and immune activation and reveals additional target pathways

Alexander Ferrena, Ranxin Zhang, Jichuan Wang, Xiang Yu Zheng, Barlas Göker, Giulia Barotti, Hasibagan Borjihan, Sung‐Suk Chae, Yungtai Lo, Hongling Zhao, Edward L. Schwartz, Rachel Offenbacher, David Mark Loeb, Rui Yang, Simone Sidoli, , Bang H. Hoang

This study uses scRNA-seq to analyze murine osteosarcoma models and identifies Skp2's role in metastasis, genomic instability, and immune activation, revealing potential therapeutic targets.

Cancer Research Communications · Mar 25, 2026Peer-reviewedCancer Biology

H2AK119ub dynamics controls hair follicle stem cell quiescence

Pooja Flora, Meng-Yen Li, Yudong Zhou, María del Pilar Hernández Mercedes, Xiang Yu Zheng, Phillip M. Galbo, Deyou Zheng, Elena Ezhkova

This study shows that H2AK119ub dynamics regulate hair follicle stem cell quiescence by repressing proliferation-promoting programs and maintaining quiescence through inhibitory niche signaling.

Nature Communications · Dec 18, 2025Peer-reviewedCell Biology

scDAPP: a comprehensive single-cell transcriptomics analysis pipeline optimized for cross-group comparison

Alexander Ferrena, Xiang Yu Zheng, Kevyn Jackson, Bang H. Hoang, Bernice E. Morrow, Deyou Zheng

scDAPP provides an automated R-based pipeline for comparative single-cell transcriptomics analysis across groups, generating comprehensive results and visualizations.

NAR Genomics and Bioinformatics · Sep 18, 2024Peer-reviewedBioinformatics