Author

Eric G. Keeler

Columbia UniversityORCID 0000-0002-9598-7148Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Ann E. McDermottiD· 1 shared Brayden Williams· 1 shared Chengming HeiD· 1 shared Chi L.L. PhamiD· 1 shared Crystal Semaan· 1 shared Emma SiereckiiD· 1 shared James C. BouweriD· 1 shared Karyn L. WildeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Ann E. McDermottORCID

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1 paper

Recent·Most cited

Structural Studies of an Anti-necroptosis Viral:Human Functional Hetero-amyloid M45:RIPK3 using SSNMR

Chengming He, Nikhil R. Varghese, Eric G. Keeler, Chi L.L. Pham, Teng Xie, Brayden Williams, Stephan Tetter, Crystal Semaan, Karyn L. Wilde, Simon H. J. Brown, James C. Bouwer, Yann Gambin, Emma Sierecki, Megan C. Steain, Ruhong Zhou, , Ann E. McDermott

This paper reports the high-resolution structure of a viral:host hetero-amyloid complex between M45 and RIPK3, revealing its mechanism of inhibiting necroptosis.

Proceedings of the National Academy of Sciences · Apr 27, 2026Peer-reviewedBiophysics