Author
MRC Laboratory of Molecular BiologyORCID 0000-0002-4175-0225Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Mikail D. Levasseur, Naohiro Terasaka, Angela Steinauer…·Donald Hilvert
The paper demonstrates splitting a 240-subunit nucleocapsid into two fragments to create a 480-subunit two-component capsid with new surface sites for functionalization.
Chengming He, Nikhil R. Varghese, Eric G. Keeler…·Ann E. McDermott
This paper reports the high-resolution structure of a viral:host hetero-amyloid complex between M45 and RIPK3, revealing its mechanism of inhibiting necroptosis.
Stephan Tetter, Nikhil R. Varghese, Alexey G. Murzin…·Benjamin Falcon
This study identifies distinct TAF15 amyloid filament structures in different FTLD-FET subtypes, leading to the renaming of the disease group as FTLD-TAF15.
Chao Qi, Bert M. Verheijen, Yasumasa Kokubo…·Michel Goedert
This study uses cryo-EM to show that tau filaments in ALS/PDC share the CTE fold, suggesting environmental causes for the disease.