Author

Letícia Alves da Silva

Medical University of ViennaORCID 0000-0002-9620-3974Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Harald H. SitteiD· 2 shared Thomas StockneriD· 2 shared Ana Sofia Alberto‐SilvaiD· 1 shared Baruch I. Kanner· 1 shared Chiara Sebastianelli-SchoditschiD· 1 shared Dániel SzöllősiiD· 1 shared Elena BossiiD· 1 shared Erika LazzariniD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPharmacology & Toxicology

Harald H. SitteORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyJournal of NeurochemistryPeer-reviewedJun 19, 2024

Bioisosteric analogs of MDMA with improved pharmacological profile

Ana Sofia Alberto‐Silva, Selina Hemmer, Hailey A. Bock…·Harald H. Sitte

This study evaluates three MDMA bioisosteres for improved pharmacological profiles, finding reduced off-target receptor activity and altered hepatic metabolism compared to MDMA.

13 citations

humanexperimental assay

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Molecular BiologybioRxivPreprintOct 10, 2023

Interaction of GAT1 with sodium ions: from efficient recruitment to stabilisation of substrate and conformation

Erika Lazzarin, Ralph Gradisch, Sophie M.C. Skopec…·Thomas Stockner

This study identifies a novel sodium recruiting site in GAT1 and shows how sodium binding stabilizes the transporter's conformation and enhances GABA uptake.

1 citation

humanstatistical model

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