Louisa Iselin

Incorporation of genome-bound cellular proteins into HIV-1 particles regulates viral infection

This study identifies 104 cellular RNA-binding proteins within HIV-1 particles, revealing their role in viral gene expression and infectivity through interactions with HIV-1 genomic RNA.

RNA binding regulation is a new dimension in the type I IFN response

This study identifies RNA-binding proteins regulated by type I IFN, revealing a new layer of antiviral response involving post-translational regulation of RNA binding.

XRN1 supplies free nucleotides to feed alphavirus replication

The paper shows that XRN1-mediated RNA decay provides nucleotides for alphavirus replication by recycling monophosphate nucleotides through the salvage pathway.

Cheap, Robust and Versatile Two-Dimensional Chromatography system for Proteomics of Nanogram Scale Samples

The paper describes a 2D chromatography system for proteomics that improves coverage and intensity with nanogram-scale samples, showing benefits for phosphoproteomics and pull-down experiments.