Ilan Davis

A myelinic channel system for motor-driven organelle transport

The paper identifies the myelinic channel system as a pathway for microtubule-dependent organelle transport in oligodendrocytes, showing its role in maintaining axonal integrity through neuronal activity and motor proteins.

Incorporation of genome-bound cellular proteins into HIV-1 particles regulates viral infection

This study identifies 104 cellular RNA-binding proteins within HIV-1 particles, revealing their role in viral gene expression and infectivity through interactions with HIV-1 genomic RNA.

Imp and Syp in vivo temporal RNA interactomes uncover networks of temporal regulators of Drosophila brain development.

XRN1 supplies free nucleotides to feed alphavirus replication

The paper shows that XRN1-mediated RNA decay provides nucleotides for alphavirus replication by recycling monophosphate nucleotides through the salvage pathway.

Dendritic localization of mRNA in Drosophila Mushroom Body Output Neurons

The paper localizes specific mRNAs in Drosophila Mushroom Body Output Neurons before and after aversive olfactory learning, showing cell-specific abundance and a transient increase in CaMKII mRNA.

Ribo-Pop: Simple, cost-effective, and widely applicable ribosomal RNA depletion

Ribo-Pop provides a simple, cost-effective, and widely applicable ribosomal RNA depletion method suitable for any organism with a sequenced genome.

Syncrip/hnRNPQ is required for activity-induced Msp300/Nesprin-1 expression and new synapse formation

This study identifies Syncrip/hnRNPQ as a regulator of activity-induced Msp300/Nesprin-1 expression and new synapse formation through local translation.

Imp/IGF2BP levels modulate individual neural stem cell growth and division through myc mRNA stability

The paper shows that Imp/IGF2BP regulates neural stem cell growth and division in Drosophila by stabilizing myc mRNA, affecting cell size and division rates.

Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation

The paper shows that larval neurons upregulate Prospero protein through alternative polyadenylation and Syncrip-mediated mRNA stabilization.

Testing models of mRNA localization reveals robustness regulated by reducing transport between cells

The paper models mRNA localization in Drosophila egg chambers and finds that transport saturation contributes to robustness against mRNA synthesis variation.

CytoCensus: mapping cell identity and division in tissues and organs using machine learning

CytoCensus is a machine learning tool for automated cell detection and division quantification in complex 3D tissues, outperforming existing software in accuracy and speed.

Single Molecule Fluorescence In Situ Hybridisation For Quantitating Post-Transcriptional Regulation In Drosophila Brains

This paper applies single-molecule FISH to study post-transcriptional regulation in Drosophila brains by analyzing mRNA distributions and co-visualizing transcripts and proteins.

Imp/Syp Temporal Gradients Govern Decommissioning Of Drosophila Neural Stem Cells

The paper shows that Imp and Syp RNA-binding protein gradients control the timing of Drosophila neuroblast decommissioning by regulating Prospero accumulation and mediator complex activity.