Author

Tetsunari Hase

Nagoya UniversityORCID 0000-0002-9653-8424Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Atsushi EnomotoiD· 1 shared Daisuke SugiyamaiD· 1 shared Fuyang Cao· 1 shared Hiroshi ArimaiD· 1 shared Hiroshi KimuraiD· 1 shared Kana Tanabe· 1 shared Katsuhiro KatoiD· 1 shared Masahide TakahashiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Atsushi EnomotoORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Local, but not circulating, complement C3 governs immune checkpoint blockade efficacy

Yuki Miyai, Yukihiro Shiraki, Daisuke Sugiyama, Yoshitaka Sato, Katsuhiro Kato, Naoya Asai, Fuyang Cao, Nobuyoshi Nagao, Kana Tanabe, Masahiro Nakatochi, Tetsunari Hase, Tetsushi Yoshikawa, Tomoko Kobayashi, Shintaro Iwama, Nobutoshi Esaki, , Atsushi Enomoto

This study shows that locally produced C3 in cancer-associated fibroblasts, not circulating C3, determines immune checkpoint blockade efficacy by modulating myeloid cell infiltration.

bioRxiv · May 12, 2025 · PreprintCancer Biology