Author

Masahide Takahashi

Fujita Health UniversityORCID 0000-0002-2803-2683Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Atsushi EnomotoiD· 1 shared Benjamin D. SimonsiD· 1 shared Daisuke SugiyamaiD· 1 shared David J. JörgiD· 1 shared Fuyang Cao· 1 shared Hiroki NakataiD· 1 shared Hiroko NakamuraiD· 1 shared Hiroshi ArimaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Atsushi EnomotoORCID

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2 papers

Recent·Most cited

Local, but not circulating, complement C3 governs immune checkpoint blockade efficacy

Yuki Miyai, Yukihiro Shiraki, Daisuke Sugiyama, Yoshitaka Sato, Katsuhiro Kato, Naoya Asai, Fuyang Cao, Nobuyoshi Nagao, Kana Tanabe, Masahiro Nakatochi, Tetsunari Hase, Tetsushi Yoshikawa, Tomoko Kobayashi, Shintaro Iwama, Nobutoshi Esaki, , Atsushi Enomoto

This study shows that locally produced C3 in cancer-associated fibroblasts, not circulating C3, determines immune checkpoint blockade efficacy by modulating myeloid cell infiltration.

bioRxiv · May 12, 2025 · PreprintCancer Biology

Self-organization of spermatogenic wave coordinates sustained sperm production in the mouse testis

Toshiyuki Sato, Yuting I. Li, David J. Jörg, Mitsuru Komeya, Hiroyuki Yamanaka, Hiroko Nakamura, Kodai Hirano, Yohei Kondo, Kazuhiro Aoki, Masahide Takahashi, Hiroki Nakata, Hiroshi Kimura, Takehiko Ogawa, Benjamin D. Simons, Shosei Yoshida

The paper uses live imaging and mathematical modeling to show how self-organization of cell turnover in mouse testes sustains sperm production through phase waves and retinoic acid signaling.

bioRxiv · Nov 3, 2024 · PreprintDevelopmental Biology