Wei Zhang

Vaccination targeting the novel endogenous tumor-associated antigen Gpr149 induces protective immunity against checkpoint inhibitor-refractory SB28 glioblastoma

This study identifies Gpr149 as an endogenous antigen in SB28 glioblastoma that can be targeted by vaccination to induce protective immunity against checkpoint inhibitor-refractory tumors.

DVT-primed neutrophils reshape the brain microenvironment to promote brain metastasis

This study shows that deep vein thrombosis (DVT) promotes brain metastasis in triple-negative breast cancer by reprogramming neutrophils to enhance vascular recruitment and NET formation.

Systemic viral vector vaccination induces brain resident memory T cells to drive anti-glioblastoma immunity

This study shows that viral vector vaccination induces brain-resident memory T cells that effectively combat glioblastoma, offering a potential therapeutic strategy.