Author

Ute A. Hoffmann

Science for Life LaboratoryORCID 0000-0002-9658-2695Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metabolomics· 1 Research Focus:protein design· 1

Frequent Co-Authors

Elton Paul HudsoniD· 3 shared Anna Zoey SchuppeiD· 2 shared Axel KnaveiD· 2 shared Emil SporreiD· 2 shared Per‐Olof SyréniD· 2 shared Rui MiaoiD· 2 shared Andreas M. EnkerliniD· 1 shared Anna KarlssoniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBiochemistry

Elton Paul HudsonORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The fitness landscape of a Form II Rubisco in a photosynthetic bacterium guides engineering of oxygen tolerance

Ute A. Hoffmann, Axel Knave, Anna Zoey Schuppe, Sebastià Capó‐Bauçà, Pere Aguiló‐Nicolau, Karen Schriever, Anna Karlsson, Michele Russo, Emil Sporre, Mami Matsuda, Rui Miao, Tomohisa Hasunuma, Jeroni Galmés, Per‐Olof Syrén, Elton Paul Hudson

The paper screens variants of a Form II Rubisco to improve oxygen tolerance, identifies key mutations, and uses a transformer model to guide engineering.

Science Advances · Sep 4, 2026Peer-reviewedBiochemistry

Deciphering the metabolic details of L-lysine toxicity in cyanobacteria

Andreas M. Enkerlin, Ute A. Hoffmann, Johanna Rapp, Rui Miao, Johannes Postma, Michael Feldbrügge, Hannes Link, Elton Paul Hudson, Khaled A. Selim

This study investigates the metabolic and physiological effects of L-lysine on Synechocystis sp. PCC 6803, identifying key genes involved in Lys resistance and metabolic disruption.

PLANT PHYSIOLOGY · Feb 27, 2026Peer-reviewedMicrobiology

A cyanobacterial screening platform for Rubisco mutant variants

Ute A. Hoffmann, Anna Zoey Schuppe, Axel Knave, Emil Sporre, Hjalmar Brismar, Elias Englund, Per‐Olof Syrén, Elton Paul Hudson

The paper develops a cyanobacterial platform to screen Rubisco mutants, identifying a variant with improved thermostability and resilience to detrimental exchanges.

ACS Synthetic Biology · Jul 7, 2025Peer-reviewedBioengineering