Author

Per‐Olof Syrén

Science for Life LaboratoryORCID 0000-0002-4066-2776Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Elton Paul HudsoniD· 3 shared Emil SporreiD· 3 shared Anna KarlssoniD· 2 shared Anna Zoey SchuppeiD· 2 shared Axel KnaveiD· 2 shared Karen SchrieveriD· 2 shared Ute A. HoffmanniD· 2 shared David KotoliD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersBiochemistry

Elton Paul HudsonORCID

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Author profile →

3 papers

Recent·Most cited

The fitness landscape of a Form II Rubisco in a photosynthetic bacterium guides engineering of oxygen tolerance

Ute A. Hoffmann, Axel Knave, Anna Zoey Schuppe, Sebastià Capó‐Bauçà, Pere Aguiló‐Nicolau, Karen Schriever, Anna Karlsson, Michele Russo, Emil Sporre, Mami Matsuda, Rui Miao, Tomohisa Hasunuma, Jeroni Galmés, Per‐Olof Syrén, Elton Paul Hudson

The paper screens variants of a Form II Rubisco to improve oxygen tolerance, identifies key mutations, and uses a transformer model to guide engineering.

Science Advances · Sep 4, 2026Peer-reviewedBiochemistry

A cyanobacterial screening platform for Rubisco mutant variants

Ute A. Hoffmann, Anna Zoey Schuppe, Axel Knave, Emil Sporre, Hjalmar Brismar, Elias Englund, Per‐Olof Syrén, Elton Paul Hudson

The paper develops a cyanobacterial platform to screen Rubisco mutants, identifying a variant with improved thermostability and resilience to detrimental exchanges.

ACS Synthetic Biology · Jul 7, 2025Peer-reviewedBioengineering

Metabolite interactions in the bacterial Calvin cycle and implications for flux regulation

Emil Sporre, Jan Karlsen, Karen Schriever, Johannes Asplund‐Samuelsson, Markus Janasch, Linnéa Strandberg, Anna Karlsson, David Kotol, Luise Zeckey, Ilaria Piazza, Per‐Olof Syrén, Fredrik Edfors, Elton Paul Hudson

The paper identifies metabolite-protein interactions in the Calvin cycle of cyanobacteria and lithoautotrophic bacteria, revealing species-specific regulation and feed-forward activation mechanisms.

Communications Biology · Sep 18, 2023Peer-reviewedSystems Biology