Emil Sporre

The paper screens variants of a Form II Rubisco to improve oxygen tolerance, identifies key mutations, and uses a transformer model to guide engineering.

borgonovo improves protein sequence accuracy from tandem mass spectra by consensus assembly of redundant de novo peptide reads, achieving 0.87 mean fixed-window identity on therapeutic antibodies.

This study identifies ppGpp-binding proteins in plants and cyanobacteria using chemoproteomics, revealing novel regulatory targets and conserved mechanisms compared to E. coli.

This study shows that immobilizing cyanobacteria in a nanocellulose matrix shifts their proteome from growth to sucrose synthesis by downregulating ribosomal proteins and upregulating carbon concentrating machinery and stress responses.

The paper develops a cyanobacterial platform to screen Rubisco mutants, identifying a variant with improved thermostability and resilience to detrimental exchanges.

The paper identifies metabolite-protein interactions in the Calvin cycle of cyanobacteria and lithoautotrophic bacteria, revealing species-specific regulation and feed-forward activation mechanisms.

This study engineered cyanobacteria to convert CO2 into secreted short-to medium-chain hydrocarbons using synthetic metabolic pathways, achieving 230 mg/L of 1-alkene with 15% carbon partitioning.