Author

Caleb Chandler

University of Colorado AnschutzORCID 0000-0002-9687-2801Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander S. DowdelliD· 1 shared Alfredo OrnelasiD· 1 shared Brittany Gomez· 1 shared Caroline H. T. HalliD· 1 shared Faiz Minhajuddin· 1 shared Geetha BhagavatulaiD· 1 shared Ian M. CartwrightiD· 1 shared Jacob A. CountessiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alexander S. DowdellORCID

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1 paper

Recent·Most cited

Metabolite mimicry identifies butyrate analogs with select protective functions in the intestinal mucosa

Alfredo Ornelas, Jacob A. Countess, Ji Yeon Kim, Rachel H. Cohen, Brittany Gomez, Rebecca L. Roer, Faiz Minhajuddin, Kiranmayee Yenugudhati Vijaya Sai, Liheng Zhou, Julia L.M. Dunn, Caleb Chandler, Philip Reigan, Ian M. Cartwright, Caroline H. T. Hall, Geetha Bhagavatula, , Sean P. Colgan

This study identifies a butyrate analog, 3-chlorobutyrate, that enhances epithelial barrier formation and is protective in colitis without affecting intestinal stem cells.

Proceedings of the National Academy of Sciences · Apr 9, 2026Peer-reviewedMolecular Biology