Author

David N. Palmer

Lincoln UniversityORCID 0000-0002-9703-5351Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Nadia L. MitchelliD· 2 shared Albert KoulmaniD· 1 shared Amit SinghiD· 1 shared Andrew M. JamesiD· 1 shared Angela SchulziD· 1 shared Benjamin JenkinsiD· 1 shared Chak Shun YuiD· 1 shared Christian Posern· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Nadia L. MitchellORCID

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2 papers

Recent·Most cited

CLN6 is a glycerophosphoglycerol epimerase in bis(monoacylglycero)phosphate biosynthesis

Pradeep Kumar Sheokand, Andrew M. James, Christian Posern, Amit Singh, Johannes Breithofer, Joe Ganellin, McKayla K. Proulx, Susannah K. Leese, Keira Turner, Denis Lacabanne, Dominik Bulfon, Benjamin Jenkins, Joris van der Kleij, Harvey E. Johnston, Samuel O. Lord, , Kasparas Petkevicius

This study identifies CLN6 as a glycerophosphoglycerol epimerase essential for BMP biosynthesis, showing its deficiency disrupts lysosomal hydrolase homeostasis and can be reversed by BMP precursor supplementation.

bioRxiv · Oct 9, 2026 · PreprintBiochemistry

Aggregation chimeras provide evidence of in vivo intercellular correction in ovine CLN6 neuronal ceroid lipofuscinosis (Batten disease)

Lucy A. Barry, Graham W. Kay, Nadia L. Mitchell, Samantha J. Murray, Nigel P. Jay, David N. Palmer

This study uses aggregation chimeras to show that CLN6 disease in sheep is not cell intrinsic, as normal-like and recovering-like chimeras show reduced neuroinflammation and neurodegeneration.

PLoS ONE · Apr 11, 2022Peer-reviewedNeuroscience