Author

Christian Posern

University Medical Center Hamburg-Eppendorf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:metabolomics· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Angela SchulziD· 3 shared Eshaan S. RawatiD· 2 shared Lena Marie Westermann· 2 shared Monther Abu-RemailehiD· 2 shared Nadia L. MitchelliD· 2 shared Peter M. van HasseltiD· 2 shared Wentao DongiD· 2 shared Albert KoulmaniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Angela SchulzORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CLN6 is a glycerophosphoglycerol epimerase in bis(monoacylglycero)phosphate biosynthesis

Pradeep Kumar Sheokand, Andrew M. James, Christian Posern, Amit Singh, Johannes Breithofer, Joe Ganellin, McKayla K. Proulx, Susannah K. Leese, Keira Turner, Denis Lacabanne, Dominik Bulfon, Benjamin Jenkins, Joris van der Kleij, Harvey E. Johnston, Samuel O. Lord, , Kasparas Petkevicius

This study identifies CLN6 as a glycerophosphoglycerol epimerase essential for BMP biosynthesis, showing its deficiency disrupts lysosomal hydrolase homeostasis and can be reversed by BMP precursor supplementation.

bioRxiv · Oct 9, 2026 · PreprintBiochemistry

Translational lipidomics reveals BMP and its precursor LPG as biomarkers for CLN5 Batten disease

Eshaan S. Rawat, Nick Manfred, Hisham N. Alsohybe, Wentao Dong, Isabelle V. Peña, Maryam Idris, Christian Posern, Lena Marie Westermann, Samantha J. Murray, Daan M. Panneman, Stefania Della Vecchia, Stefano Doccini, Maria Marchese, Filippo Maria Santorelli, Peter M. van Hasselt, , Monther Abu-Remaileh

This study identifies BMP and LPG as biomarkers for CLN5 Batten disease using lipidomics, showing their depletion and elevation in disease models and patient samples.

bioRxiv · Mar 21, 2026 · PreprintCell Biology

Tagless LysoIP method for molecular profiling of lysosomal content in clinical samples

Daniel Saarela, Paweł Lis, Sara Gomes, Raja Sekhar Nirujogi, Wentao Dong, Eshaan S. Rawat, Sophie Glendinning, Karolina Zeneviciute, Enrico Bagnoli, Rotimi Yemi Fasimoye, Cindy Lin, Kwamina Nyame, Fanni Annamária Boros, Friederike Zunke, Frédéric Lamoliatte, , Esther M. Sammler

The paper develops a tagless LysoIP method to isolate lysosomes from clinical samples and human cell lines, revealing glycerophosphodiesters as potential biomarkers for lysosomal storage disorders.

Journal of Clinical Investigation · Dec 26, 2024Peer-reviewedCell Biology