Yajun Zhang

Mature interneuron subtypes arise from distinct spatial and temporal subdomains within the caudal ganglionic eminence

The paper investigates the spatial and temporal origins of interneuron subtypes in the caudal ganglionic eminence (CGE) and shows that specific subtypes arise from distinct CGE subdomains with stable spatial biases over time.

NMDAR-mediated transcriptional control of gene expression during the development of medial ganglionic eminence-derived interneurons

This study identifies Grin1 as a key regulator of subtype-specific gene expression in MGE-derived interneurons, linking NMDAR signaling to neurodevelopmental disorders like schizophrenia.

Single nucleus RNA-sequencing defines unexpected diversity of cholinergic neuron types in the adult mouse spinal cord

The paper uses single nucleus RNA sequencing to identify diverse cholinergic neuron types in the adult mouse spinal cord, revealing distinct transcriptomic classes of visceral and skeletal motor neurons.

Emergence of Non-Canonical Parvalbumin-Containing Interneurons in Hippocampus of a Murine Model of Type I Lissencephaly

The paper examines LIS1 mutation effects on PV+INTs in mouse hippocampus, identifying a non-canonical intermediate spiking subset linked to seizures.

New and improved GRAB fluorescent sensors for monitoring dopaminergic activity in vivo

The paper develops and optimizes GRABDA fluorescent sensors to monitor dopaminergic activity with high sensitivity and resolution in vivo.

Morning and Evening Circadian Pacemakers Independently Drive Premotor Centers via a Specific Dopamine Relay

The paper identifies a circadian pathway in Drosophila where morning and evening oscillators drive pre-motor centers via specific dopaminergic neurons, resulting in a two-peak locomotor activity pattern.