This study identifies distinct roles of TRAP and TRP1 adhesins in Plasmodium sporozoite motility and invasion, showing differential signaling requirements for gliding and transmission.

bioRxiv · May 26, 2026 · PreprintCell Biology

A genetically encoded marker for imaging membranes of Plasmodium

Leah Zink, Viola Reuschenbach, Samy Sid Ahmed, Muriel Lauer, Jana Niethammer, Aiste Kudulyte, Katharina Zorko, O. Fackler, Franziska Hentzschel, Markus Ganter

The paper introduces FLUMMI, a peptide marker for imaging internal membranes in Plasmodium without affecting viability, and shows its compatibility with live-cell and expansion microscopy.

bioRxiv · Oct 24, 2025 · PreprintMicrobiology

paraCell: A novel software tool for the interactive analysis and visualization of standard and dual host-parasite single cell RNA-Seq data

Edward Agboraw, William A. Haese-Hill, Franziska Hentzschel, Emma M. Briggs, Dana Aghabi, Anna Heawood, Clare R. Harding, Brian R Shiels, Kathryn Crouch, Domenico Somma, Thomas D. Otto

paraCell provides an interactive tool for analyzing and visualizing host-parasite single-cell RNA-Seq data without requiring programming skills.

Nucleic Acids Research · Feb 8, 2025Peer-reviewedBioinformatics