Katherine M. Kichula

This paper introduces scTAPAS, a method to reconstruct donor genotypes from scRNA-seq data, enabling eQTL and HLA-TCR analysis without conventional genotyping.

KIR*BLOOM improves KIR genotyping accuracy by modeling copy number and sequencing errors, achieving high precision and recall on whole-genome sequencing data.

The paper tests HLA dissimilarity in Himba pastoralists and finds no evidence of disassortative mating or fitness benefits from HLA differences in either arranged or chosen partnerships.

The paper completes six MHC haplotypes, including DR1, DR4, and structurally variable C4 regions, improving reference panels for immunogenomics analysis.