Author

David L. Bark

Washington University in St. LouisORCID 0000-0002-9865-6176Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Abigail AjaneliD· 1 shared Adam BalutowskiiD· 1 shared Alice LiuiD· 1 shared Ashutosh KumariD· 1 shared Chloe Grace MeyeriD· 1 shared Daniel J. Lerner· 1 shared Gavriel Brown· 1 shared Haixia ZhangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Abigail AjanelORCID

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1 paper

Recent·Most cited

Cell BiologyBloodPeer-reviewedJun 20, 2025

LRRC8 complexes are adenosine nucleotide release channels regulating platelet activation and arterial thrombosis

John D. Tranter, Ryan T. Mikami, Ashutosh Kumar…·Rajan Sah

This study identifies LRRC8 complexes as ATP/ADP release channels in platelets that regulate thrombosis by modulating calcium and PI3K-AKT signaling through P2X1, P2Y1, and P2Y12 receptors.

12 citationstop 2%

mouseproteomics

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