Author

Daniel J. Lerner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

John D. TranteriD· 2 shared Prakash ArullampalamiD· 2 shared Rajan SahiD· 2 shared Tarek Mohamed Abd El‐AziziD· 2 shared Yonghui ZhaoiD· 2 shared Abigail AjaneliD· 1 shared Adam BalutowskiiD· 1 shared Alice LiuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCell Biology

John D. TranterORCID

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2 papers

Recent·Most cited

Endothelial LRRC8C associates with LRRC8A and LRRC8B to regulate vascular reactivity and blood pressure

Qiujun Yu, Yonghui Zhao, Joshua M Maurer, Prakash Arullampalam, Nathaniel John, John D. Tranter, Tarek Mohamed Abd El‐Aziz, Michelle Lin, Daniel J. Lerner, Carmen M. Halabi, Rajan Sah

This study identifies LRRC8C as a non-redundant component of the endothelial LRRC8 complex that regulates vascular reactivity and blood pressure.

Hypertension · Feb 4, 2026Peer-reviewedCell Biology

LRRC8 complexes are adenosine nucleotide release channels regulating platelet activation and arterial thrombosis

John D. Tranter, Ryan T. Mikami, Ashutosh Kumar, Gavriel Brown, Tarek Mohamed Abd El‐Aziz, Yonghui Zhao, Prakash Arullampalam, Katrina J. Ashworth, Vishwanath Jha, Nihil Abraham, Chloe Grace Meyer, Abigail Ajanel, Litao Xie, Yongmei Feng, Juan Hong, , Rajan Sah

This study identifies LRRC8 complexes as ATP/ADP release channels in platelets that regulate thrombosis by modulating calcium and PI3K-AKT signaling through P2X1, P2Y1, and P2Y12 receptors.

Blood · Jun 20, 2025Peer-reviewedCell Biology