Author

Huihui Kuang

New York Structural Biology CenterORCID 0000-0002-9891-1747Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 1 Organism:yeast· 1

Frequent Co-Authors

Adam G. SchrumiD· 1 shared Alex KentsisiD· 1 shared Andrej ŠaliiD· 1 shared Andrew Santiago‐FrangosiD· 1 shared Bingbing WaniD· 1 shared Blake WiedenheftiD· 1 shared Bret D. UleryiD· 1 shared Brett T Rygelski· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBioengineering

Adam G. SchrumORCID

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3 papers

Recent·Most cited

Structures reveal how the Cas1-2/3 integrase captures, delivers, and integrates foreign DNA into CRISPR loci

William S. Henriques, Jarrett Bowman, Laina N. Hall, Colin C. Gauvin, Hui Alex Wei, Huihui Kuang, Christina M. Zimanyi, Edward T. Eng, Andrew Santiago‐Frangos, Blake Wiedenheft

The paper determines structures of the Cas1-2/3 complex to elucidate how it captures, delivers, and integrates foreign DNA into CRISPR loci.

Structure · Oct 10, 2025Peer-reviewedMolecular Biology

Adjuvant Delivery Method and Nanoparticle Charge Influence Peptide Amphiphile Micelle Vaccine Bioactivity

Rui Zhang, Brett T Rygelski, Luke E. Kruse, Josiah D. Smith, Xiaofei Wang, Brittany N. Allen, Jake S. Kramer, Gracen F. Seim, Trent J. Faulkner, Huihui Kuang, Efrosini Kokkoli, Adam G. Schrum, Bret D. Ulery

This study investigates how adjuvant delivery methods and nanoparticle charge affect the bioactivity of peptide amphiphile micelle vaccines, showing improved dendritic cell activation with electrostatic complexation.

bioRxiv · Jun 10, 2024 · PreprintBioengineering

Integrative analysis reveals unique features of the Smc5/6 complex

You Yu, Shibai Li, Zheng Ser, Tanmoy Sanyal, Koyi Choi, Bingbing Wan, Huihui Kuang, Andrej Šali, Alex Kentsis, Dinshaw J. Patel, Xiaolan Zhao

The paper presents an integrative structural analysis of the Smc5/6 complex in budding yeast, revealing unique structural features and functional interactions among its subunits.

Proceedings of the National Academy of Sciences · May 3, 2021Peer-reviewedMolecular Biology