Author

Osama E. Demerdash

Cold Spring Harbor LaboratoryORCID 0000-0002-9896-2077Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:yeast· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Bruce StillmaniD· 2 shared Narges Zali· 2 shared Aktan AlpsoyiD· 1 shared Amanda M. CafieroiD· 1 shared Christopher R. VakociD· 1 shared Claudia TonelliiD· 1 shared Damianos S. SkopelitisiD· 1 shared David A. TuvesoniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMolecular Biology

Bruce StillmanORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 5, 2026

Evolution of Origin Sequence and Recognition for Licensing of Eukaryotic DNA Replication

Jack Bauer, Narges Zali, Om Prakash Chouhan…·Bruce Stillman

The paper compares origin recognition mechanisms in yeast and human cells, revealing evolutionary differences in DNA replication initiation.

DOI 10.64898/2026.03.10.710760

𝕏 PostBluesky

GenomicsNAR Genomics and BioinformaticsPeer-reviewedOct 7, 2025

Genome sequence assembly and annotation of MATA and MATB strains of Yarrowia lipolytica

Narges Zali, Osama E. Demerdash, Kapeel M. Chougule…·Bruce Stillman

The paper presents high-quality genome assemblies and annotations for two Yarrowia lipolytica strains, using a combination of short-read and long-read sequencing technologies.

2 citations

yeastwhole-genome sequencing

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Cancer BiologyCancer DiscoveryPeer-reviewedJul 25, 2024

MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer

Olaf Klingbeil, Damianos S. Skopelitis, Claudia Tonelli…·Christopher R. Vakoc

This study identifies MARK2/3 as essential kinases for YAP/TAZ function in cancer and shows their inhibition can restore Hippo pathway tumor suppression.

31 citationstop 4%

humanproteomics

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