Author

Wenjing Qi

University of FreiburgORCID 0000-0002-9287-5837Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Ralf BaumeisteriD· 3 shared Wei YangiD· 3 shared Bettina WarscheidiD· 2 shared Ekkehard SchulzeiD· 2 shared Erika Donner von Gromoff· 2 shared Jennifer SchwarziD· 2 shared Qian ZhaoiD· 2 shared Angelica Trentino· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersMolecular Biology

Ralf BaumeisterORCID

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3 papers

Recent·Most cited

Targeting the paralog protein for degradation accounts for the opposite roles of NRBP1 and NRBP2 in regulating LINE1 retrotransposition

Wei Yang, Shaobo Cong, Ruoyao Li, Jennifer Schwarz, Thilo Schulze, Raban A Gevelhoff, Xinyan Chen, Sara Ullrich, Kristina Falkenstein, Denis Ott, Pia Eixmann, Angelica Trentino, Antje Thien, Thiérry Heidmann, Ekkehard Schulze, , Wenjing Qi

The paper shows NRBP1 and NRBP2 oppositely regulate LINE1 retrotransposition through proteasome-mediated degradation of NRBP1 by NRBP2, with NRBP2's regulatory function evolving later.

Nature Communications · Jul 11, 2025Peer-reviewedCell Biology

Pseudokinase HPO-11 inhibits nonsense-mediated decay to ensure genome stability in C. elegans

Qian Zhao, Erika Donner von Gromoff, Wei Yang, Jennifer Schwarz, Lena Sophie Tittel, Ekkehard Schulze, Bettina Warscheid, Ralf Baumeister, Wenjing Qi

This study identifies HPO-11 as a pseudokinase that inhibits nonsense-mediated decay (NMD) to maintain genome stability in C. elegans by preventing R-loop accumulation and DNA damage.

bioRxiv · Sep 4, 2022 · PreprintMolecular Biology

A secreted endoribonuclease ENDU-2 from the soma protects germline immortality in C. elegans

Wenjing Qi, Erika Donner von Gromoff, Fan Xu, Qian Zhao, Wei Yang, Dietmar Pfeifer, Wolfgang Maier, Lijiang Long, Ralf Baumeister

This study identifies ENDU-2, a secreted RNase in C. elegans, that maintains germline immortality by regulating mRNA abundance and preventing soma-specific gene misexpression in the germline.

Nature Communications · Feb 24, 2021Peer-reviewedMolecular Biology