Author

Seungyoon B. Yu

University of California San DiegoORCID 0000-0002-9910-6029Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Seungyoon B. Yu1 paper · Denali Therapeutics (United States)

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Gülçin PekkurnaziD· 3 shared Ahmed A. AbushawishiD· 2 shared Andrew J. ZhangiD· 2 shared Haoming WangiD· 2 shared Majid GhassemianiD· 2 shared Richard G. SáncheziD· 2 shared Abhishek SingharoyiD· 1 shared Alaa Abdel LatifiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Gülçin PekkurnazORCID

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Author profile →

3 papers

Recent·Most cited

Neuronal activity-driven O-GlcNAcylation promotes mitochondrial plasticity

Seungyoon B. Yu, Haoming Wang, Richard G. Sánchez, Natasha M. Carlson, Khanh Quynh Nguyen, Andrew J. Zhang, Zachary D. Papich, Ahmed A. Abushawish, Zachary D. Whiddon, Weronika Matysik, Jie Zhang, Thomas C. Whisenant, Majid Ghassemian, John N. Koberstein, Melissa L. Stewart, , Gülçin Pekkurnaz

This study shows that neuronal activity increases mitochondrial O-GlcNAcylation, which helps neurons meet energy demands based on fuel availability.

Developmental Cell · Jun 5, 2024Peer-reviewedNeuroscience

Functional Organization of Glycolytic Metabolon on Mitochondria

Haoming Wang, John Vant, Youjun Wu, Richard G. Sánchez, Mary Lauren Micou, Andrew J. Zhang, Vincent Luczak, Seungyoon B. Yu, Mirna Jabbo, Seokjun Yoon, Ahmed A. Abushawish, Majid Ghassemian, Eric R. Griffis, Marc Hammarlund, Abhishek Singharoy, Gülçin Pekkurnaz

This study identifies OGT-mediated O-GlcNAcylation of HK1 as a mechanism regulating glycolytic metabolon assembly on mitochondria, enhancing ATP production and synaptic function.

bioRxiv · Aug 26, 2023 · PreprintNeuroscience

Deep Learning-Based Point-Scanning Super-Resolution Imaging

Linjing Fang, Fred Monroe, Sammy Weiser Novak, Lyndsey M. Kirk, Cara R. Schiavon, Seungyoon B. Yu, Tong Zhang, Melissa Wu, Kyle Kastner, Alaa Abdel Latif, Zijun Lin, Andrew Shaw, Yoshiyuki Kubota, John M. Mendenhall, Zhao Zhang, , Uri Manor

This paper introduces a deep learning method to enhance the resolution and speed of point-scanning imaging systems by restoring undersampled images.

Nature Methods · Mar 8, 2021Peer-reviewedBioinformatics