Gülçin Pekkurnaz

This study develops an agent-based model to show how mitochondrial shape, mechanics, and fission-fusion dynamics influence axonal transport and structural integrity.

This study identifies mitochondrial-derived double-stranded RNA as a source of RNA stress in aged neurons, which activates the ISR through PKR and contributes to neurodegeneration.

This study shows that neuronal activity increases mitochondrial O-GlcNAcylation, which helps neurons meet energy demands based on fuel availability.

This study identifies OGT-mediated O-GlcNAcylation of HK1 as a mechanism regulating glycolytic metabolon assembly on mitochondria, enhancing ATP production and synaptic function.

The paper develops a 3D reaction-diffusion model to study how mitochondria-endoplasmic reticulum contact sites regulate calcium and ATP dynamics in postsynaptic spines.

This paper introduces a deep learning method to enhance the resolution and speed of point-scanning imaging systems by restoring undersampled images.