The paper investigates the role of bursting and non-bursting neural activity in functional brain networks, demonstrating that correcting for power bias reveals the importance of brain rhythms in network connectivity.

Imaging Neuroscience · Jan 1, 2024Peer-reviewedNeuroscience

Functional identification of language-responsive channels in individual participants in MEG investigations

Mathias Huybrechts, Rose Bruffaerts, Alvince Le Arnz Pongos, Cory Shain, Benjamin Lipkin, Matthew Siegelman, Vincent Wens, Martin Sjøgård, Idan Blank, Serge Goldman, Xavier De Tiège, Evelina G. Fedorenko

The paper identifies language-responsive neural channels in individual participants using MEG, showing spatial stability within individuals but variability across individuals, leading to greater sensitivity in analyses.

bioRxiv · Mar 23, 2023 · PreprintNeuroscience

Cortical tracking of lexical speech units in a multi-talker background is immature in school-aged children

Maxime Niesen, Mathieu Bourguignon, Julie Bertels, Marc Vander Ghinst, Vincent Wens, Serge Goldman, Xavier De Tiège

This study shows that school-aged children have reduced cortical tracking of linguistic units in speech, especially in noisy environments, compared to adults.

NeuroImage · Nov 30, 2022Peer-reviewedNeuroscience

Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism

Mírian Romitti, Adrien Tourneur, Bárbara F. Fonseca, Gilles Doumont, Pierre Gillotay, Xiao-Hui Liao, Sema Elif Eski, Gaëtan Van Simaeys, Laura Chomette, Hélène Lasolle, Olivier Monestier, Dominika Figini Kasprzyk, Vincent Detours, Sumeet Pal Singh, Serge Goldman, , Sabine Costagliola

This study generates transplantable human thyroid organoids from embryonic stem cells that restore thyroid hormone levels in athyreotic mice.

Nature Communications · Nov 17, 2022Peer-reviewedDevelopmental Biology

Microstates and power envelope hidden Markov modeling probe bursting brain activity at different timescales

Nicolas Coquelet, Xavier De Tiège, Liliia Roshchupkina, Philippe Peigneux, Serge Goldman, Mark W. Woolrich, Vincent Wens

This study compares microstate analysis and hidden Markov modeling of MEG/EEG data to show they capture different spatial and temporal aspects of brain activity.

NeuroImage · Dec 22, 2021Peer-reviewedNeuroscience

Alpha peak frequency is linked to episodic memory impairment in pathological aging

Delphine Puttaert, Vincent Wens, Patrick Fery, Antonin Rovaï, Nicola Trotta, Nicolas Coquelet, Sandra De Breucker, Niloufar Sadeghi, Tim Coolen, Serge Goldman, Philippe Peigneux, Jean‐Christophe Bier, Xavier De Tiège

This study links reduced alpha peak frequency to episodic memory impairment in aging, showing correlations with encoding efficiency and hippocampal function.

Frontiers in Aging Neuroscience · Aug 12, 2021Peer-reviewedNeuroscience

Spectro-temporal neural dynamics during sentence completion

Tim Coolen, Alexandru Mihai Dumitrescu, Vincent Wens, Mathieu Bourguignon, Gustavo Lucena Gómez, Antonin Rovaï, Niloufar Sadeghi, Charline M. Urbain, Serge Goldman, Xavier De Tiège

This study uses MEG to analyze spectro-temporal neural dynamics during sentence completion, identifying distinct oscillatory patterns and their spatial characteristics.

bioRxiv · Jul 1, 2021 · PreprintNeuroscience

Changes in electrophysiological static and dynamic human brain functional architecture from childhood to late adulthood

Nicolas Coquelet, Vincent Wens, Alison Mary, Maxime Niesen, Delphine Puttaert, Mariagrazia Ranzini, Marc Vander Ghinst, Mathieu Bourguignon, Philippe Peigneux, Serge Goldman, Mark W. Woolrich, Xavier De Tiège

This study examines age-related changes in resting-state brain function from childhood to late adulthood using magnetoencephalography, finding increased integration and stability in development and reduced integration in aging.

Scientific Reports · Nov 4, 2020Peer-reviewedNeuroscience

Alterations in resting-state network dynamics along the Alzheimer's disease continuum: a combined MEG-PET/MR approach

Delphine Puttaert, Nicolas Coquelet, Vincent Wens, Philippe Peigneux, P. Fery, Antonin Rovaï, Nicola Trotta, J C Bier, Serge Goldman, Xavier De Tiège

This study examines how resting-state network dynamics change in Alzheimer's disease using MEG and PET/MR, finding altered posterior DMN activation patterns in AD patients linked to structural and metabolic changes.

bioRxiv · May 18, 2020 · PreprintNeuroscience

Intrinsic/extrinsic duality of large-scale neural functional integration in the human brain

Martin Sjøgård, Mathieu Bourguignon, Lars Costers, Alexandru Mihai Dumitrescu, Tim Coolen, Liliia Roshchupkina, Florian Destoky, Julie Bertels, Maxime Niesen, Marc Vander Ghinst, Jeroen Van Schependom, Guy Nagels, Charline M. Urbain, Philippe Peigneux, Serge Goldman, , Vincent Wens

The paper identifies two modes of neural communication in the human brain—extrinsic coupling via phase synchronization and intrinsic integration via amplitude correlation—during rest and tasks.

bioRxiv · Apr 21, 2020 · PreprintNeuroscience