Author

Lito L. Appell

Emory UniversityORCID 0000-0002-9965-7613Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Adam D. GracziD· 1 shared Antoine R. GleizesiD· 1 shared Felipe TakaesuiD· 1 shared Joseph LeeiD· 1 shared Nick BarkeriD· 1 shared Nicolas V. JantoiD· 1 shared Sarah F. WebsteriD· 1 shared Siyang SuniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

Adam D. GraczORCID

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1 paper

Recent·Most cited

Lgr5+ intestinal stem cells are required for organoid survival after genotoxic injury

Joseph Lee, Antoine R. Gleizes, Nicolas V. Janto, Lito L. Appell, Siyang Sun, Felipe Takaesu, Sarah F. Webster, Taylor Hailstock, Nick Barker, Adam D. Gracz

This study shows that Lgr5+ intestinal stem cells are necessary for organoid survival after genotoxic injury, despite fISC gene activation occurring at both low and high doses of doxorubicin.

Development · Nov 6, 2024Peer-reviewedCell Biology