Manon Galoppin

Vitamin D differentially modulates effector and regulatory T-cell migration across the blood-brain barrier

This study shows that vitamin D reduces effector T-cell migration across the blood-brain barrier while preserving regulatory T-cell entry, potentially benefiting multiple sclerosis patients.

Ketogenic interventions restore cognition and modulate peripheral metabolic dysfunctions in Alzheimer's disease mouse models

This study shows that two ketogenic diets improve cognition and metabolic health in Alzheimer's disease mouse models, with distinct effects on peripheral metabolism.

Central inhibition of Stearoyl-CoA Desaturase has minimal effects on the peripheral metabolic symptoms of the 3xTg Alzheimer's disease mouse model

This study shows that inhibiting Stearoyl-CoA Desaturase in the brain of 3xTg-AD mice improves cognitive function without affecting peripheral metabolic symptoms.

CITE-seq reveals inhibition of NF-kB pathway in B cells from vitamin D-treated multiple sclerosis patients

The paper uses CITE-seq to analyze B cells from vitamin D-treated MS patients, identifying NF-kB pathway inhibition as a potential mechanism for vitamin D's protective effects.

Syndecan-1 as specific cerebrospinal fluid biomarker of multiple sclerosis

The paper identifies Syndecan-1 as a specific cerebrospinal fluid biomarker for multiple sclerosis, improving diagnostic and prognostic accuracy compared to existing markers.