Author

Alexandra Benchoua

Institut des Cellules Souches pour le Traitement et l'Étude des Maladies MonogéniquesORCID 0000-0002-9980-6471Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Laure ChatrousseiD· 3 shared Adeline Beuriot· 1 shared Amandine Thibaudeau· 1 shared Amélie Weiss· 1 shared Aurore VuideliD· 1 shared Azania Abatan· 1 shared Cécile MartinatiD· 1 shared Christina B. JacobiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersPathology

Laure ChatrousseORCID

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3 papers

Recent·Most cited

Cortical organoids from congenital DM1 PSCs reveal MBNL-dependent corticogenesis defects and enable preclinical testing of therapeutic compounds

Azania Abatan, Jérôme Polentes, Margot Bouquier, Adeline Beuriot, Olivier Chose, Hamel Mahiou, Lina El Kassar, Karine Giraud-Triboult, Laure Chatrousse, Alexandra Benchoua, Stéphanie Tomé, Geneviève Gourdon, Mário Gomes-Pereira, Sandrine Baghdoyan, Cécile Martinat

This study uses cortical organoids from congenital DM1 patient cells to show MBNL-dependent neurodevelopmental defects and test therapeutic compounds.

bioRxiv · Jul 27, 2026 · PreprintPathology

Advanced human cerebral organoids as a model for investigating glioma stem cell interactions with microglia and vascular cells and response to radiotherapy

Jérémy Raguin, Noa Legrand, Thierry Kortulewski, Oriane Bergiers, Christine Granotier, Laure Chatrousse, Alexandra Benchoua, Laurent Gauthier, François Dominique Boussin, Marc‐André Mouthon

This paper develops a vascularized cerebral organoid model with microglia to study glioma stem cell interactions and radiotherapy response.

Cell Reports Methods · May 5, 2026Peer-reviewedCancer Biology

Pharmacological modulation of developmental and synaptic phenotypes in human SHANK3 deficient stem cell-derived neuronal models

Amandine Thibaudeau, Karen Schmitt, Louise François, Laure Chatrousse, David Hoffmann, Loïc Cousin, Amélie Weiss, Aurore Vuidel, Christina B. Jacob, Peter Sommer, Alexandra Benchoua, Johannes H. Wilbertz

This study screens small molecules in SHANK3-deficient neuronal models to identify compounds that rescue developmental and synaptic defects in Phelan-McDermid syndrome.

Translational Psychiatry · Jun 10, 2024Peer-reviewedNeuroscience