Author

Pauline Cassart

McGill University Health CentreORCID 0000-0002-9985-1571Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Erwin SchurriD· 2 shared Wilian Correa-MacedoiD· 2 shared A Seeger· 1 shared AK Coussens· 1 shared Alain PacisiD· 1 shared Anne Dumaine· 1 shared Barbara KalsdorfiD· 1 shared Ben LoosiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenetics

Erwin SchurrORCID

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2 papers

Recent·Most cited

Altered neutrophil extracellular traps in response to Mycobacterium tuberculosis in persons living with HIV with no previous TB and negative TST and IGRA

Elouise E. Kroon, Wilian Correa-Macedo, Roger G. Evans, A Seeger, Louise Engelbrecht, Jurgen Kriel, Ben Loos, Naomi Okugbeni, M Orlova, Pauline Cassart, Craig John Kinnear, GC Tromp, Marlo Möller, RJ Wilkinson, AK Coussens, , Eileen Garner Hoal

The paper compares the neutrophil response to Mycobacterium tuberculosis infection between HIV+ individuals with and without TB history, finding distinct gene expression and NETosis patterns in those without TB.

bioRxiv · Apr 19, 2023 · PreprintGenetics

Epigenetic impairment and blunted transcriptional response to Mycobacterium tuberculosis of alveolar macrophages from persons living with HIV

Wilian Correa-Macedo, Vinicius M. Fava, Marianna Orlova, Pauline Cassart, Ron Olivenstein, Joaquín Sanz, Yong Zhong Xu, Anne Dumaine, Renata Sindeaux, Vania Yotova, Alain Pacis, Josée Girouard, Barbara Kalsdorf, Christoph Lange, Jean‐Pierre Routy, , Erwin Schurr

The paper investigates how HIV and antiretroviral therapy affect the transcriptional and epigenetic response of alveolar macrophages to Mycobacterium tuberculosis.

Journal of Clinical Investigation · Sep 2, 2021Peer-reviewedGenetic & Genomic Medicine