Author

Barbara Kalsdorf

Research Center Borstel - Leibniz Lung CenterORCID 0000-0002-5976-3470Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 1 Genetic & Genomic Medicine· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Christoph G. LangeiD· 2 shared Abigail Savietto· 1 shared Aditi BatraiD· 1 shared Alain PacisiD· 1 shared Anne Dumaine· 1 shared Badri N. DubeyiD· 1 shared Dan I. AnderssoniD· 1 shared Daniel Schütz· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

Christoph G. LangeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Robust antibiotic sensitization of pathogenic Pseudomonas aeruginosa via negative hysteresis in the cell envelope

Florian Buchholz, Lina M. Upterworth, Leif Tüeffers, Espen Elias Groth, Kira Haas, Daniel Schütz, Abigail Savietto, Aditi Batra, Surajit Pal, Samarpita Banerjee, Badri N. Dubey, Sören Franzenburg, Barbara Kalsdorf, Klaus Friedrich Rabe, Dennis Nurjadi, , Hinrich Schulenburg Y

The paper identifies negative hysteresis as a robust phenomenon in Pseudomonas aeruginosa that enhances antibiotic efficacy through increased aminoglycoside uptake after beta-lactam treatment.

Nature Communications · Mar 26, 2026Peer-reviewedEvolutionary Biology

Serratia sp. dominates the lung microbiome of patients with tuberculosis and non-tuberculous mycobacterial lung diseases

Meriem Belheouane, Barbara Kalsdorf, Stefan Niemann, Karoline I. Gaede, Christoph G. Lange, Jan Heyckendorf, Matthias Merker

This study identifies Serratia sp. as a dominant genus in the lung microbiome of TB and NTM-LD patients, with specific ASVs associated with disease states.

PLoS ONE · Jun 26, 2025Peer-reviewedMicrobiology

Epigenetic impairment and blunted transcriptional response to Mycobacterium tuberculosis of alveolar macrophages from persons living with HIV

Wilian Correa-Macedo, Vinicius M. Fava, Marianna Orlova, Pauline Cassart, Ron Olivenstein, Joaquín Sanz, Yong Zhong Xu, Anne Dumaine, Renata Sindeaux, Vania Yotova, Alain Pacis, Josée Girouard, Barbara Kalsdorf, Christoph Lange, Jean‐Pierre Routy, , Erwin Schurr

The paper investigates how HIV and antiretroviral therapy affect the transcriptional and epigenetic response of alveolar macrophages to Mycobacterium tuberculosis.

Journal of Clinical Investigation · Sep 2, 2021Peer-reviewedGenetic & Genomic Medicine