Author

Alessio Strano

University College LondonORCID 0000-0002-7364-6553Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Organism:Drosophila· 1

Frequent Co-Authors

Frederick J. LiveseyiD· 3 shared Lewis EvansiD· 2 shared Alastair D. ReithiD· 1 shared Alexander Shakeel BatesiD· 1 shared Amy McCarthy· 1 shared Andrew R. Bassett· 1 shared Ashley Campbell· 1 shared Ben SutcliffeiD· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Frederick J. LiveseyORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Trisomy 21 impairs synchronized activity and connectivity in developing human Down syndrome cortical excitatory neuron networks

Manuel Peter, Raquel Real, Alessio Strano, Hugh P. C. Robinson, Mark A. Smith, Samuel J. Barnes, Tania Dutta, Vincenzo De Paola, Frederick J. Livesey

bioRxiv · Dec 27, 2024 · PreprintNeuroscience

Whole genome CRISPR screens identify a LRRK2-regulated pathway for extracellular tau uptake by human neurons

Lewis Evans, Alessio Strano, Eleanor J. Tuck, Ashley Campbell, James C. Smith, Christy Hung, Tiana S. Behr, Bernardino Francesco Ghetti, Benjamin Falcon, Emre Karakoç, Francesco Iorio, Alastair D. Reith, Andrew R. Bassett, Frederick J. Livesey

The paper identifies LRRK2-regulated pathways for extracellular tau uptake in human neurons using CRISPR screens, showing LRRK2's role in monomeric tau endocytosis.

bioRxiv · Aug 11, 2020 · PreprintNeuroscience

Molecular and cellular pathology of monogenic Alzheimer's disease at single cell resolution

Federica Marinaro, Moritz Haneklaus, Zhechun Zhang, Alessio Strano, Lewis Evans, Louis‐François Handfield, Natalie Sarah Ryan, Nick C. Fox, Martin Hemberg, Sharad Ramanathan, Frederick J. Livesey

The paper constructs a single-cell atlas of the frontal cortex in early-onset monogenic Alzheimer's disease to identify cellular and molecular changes in disease mechanisms.

bioRxiv · Jul 14, 2020 · PreprintNeuroscience

BAcTrace a new tool for retrograde tracing of neuronal circuits

Sebastian Cachero, Marina Gkantia, Alexander Shakeel Bates, Shahar Frechter, Laura Blackie, Amy McCarthy, Ben Sutcliffe, Alessio Strano, Yoshinori Aso, Gregory S.X.E. Jefferis

BAcTrace is a new genetically encoded tool for retrograde neuronal tracing validated in Drosophila olfactory circuits.

bioRxiv · Jan 24, 2020 · PreprintNeuroscience