Author

Keiko Nakayama

Tohoku UniversityORCID 0000-0003-0134-6401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Hironari NishizawaiD· 2 shared Kazuhiko IgarashiiD· 2 shared Mitsuyo MatsumotoiD· 2 shared Tadashi NakagawaiD· 2 shared Akari Endo· 1 shared Akihiko MutoiD· 1 shared Akira Okoshi· 1 shared Ayako NakanomeiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Hironari NishizawaORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 7, 2025

Metabolic cell death of labile iron deficiency as a vulnerability of head and neck squamous cancer cells evaded by BACH1

Masahiro Rokugo, Kazuki Nakamura, Mitsuyo Matsumoto…·Kazuhiko Igarashi

This study shows that BACH1 maintains labile iron levels in HNSCC cells, preventing metabolic cell death and enabling proliferation, and that BACH1 inhibition enhances the effect of tipifarnib.

DOI 10.1101/2025.04.07.647470

humanbulk RNA-seq

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NeurosciencebioRxivPreprintOct 22, 2024

ALS-associated RNA binding proteins converge on UNC13A transcription through regulation of REST

Yasuaki Watanabe, Naoki Suzuki, Tadashi Nakagawa…·Keiko Nakayama

The paper shows that three ALS-associated RBPs regulate UNC13A transcription by targeting REST, highlighting their role in synaptic integrity and ALS pathogenesis.

DOI 10.1101/2024.10.22.619761

humanbulk RNA-seq

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BiochemistryInternational Journal of Molecular SciencesPeer-reviewedApr 9, 2024

TANK binding kinase 1 promotes BACH1 degradation through both phosphorylation-dependent and -independent mechanisms without relying on heme and FBXO22

Liang Liu, Mitsuyo Matsumoto, Miki Watanabe‐Matsui…·Kazuhiko Igarashi

7 citations

humanprotein sequence

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