Author

Mitsuyo Matsumoto

Tohoku UniversityORCID 0000-0002-2918-9893Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

Hironari NishizawaiD· 2 shared Kazuhiko IgarashiiD· 2 shared Keiko NakayamaiD· 2 shared Akari Endo· 1 shared Akihiko MutoiD· 1 shared Akira Okoshi· 1 shared Ayako NakanomeiD· 1 shared Bert K. K. CallensiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Hironari NishizawaORCID

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2 papers

Recent·Most cited

Metabolic cell death of labile iron deficiency as a vulnerability of head and neck squamous cancer cells evaded by BACH1

Masahiro Rokugo, Kazuki Nakamura, Mitsuyo Matsumoto, Akari Endo, Long C. Nguyen, Hironari Nishizawa, Ryohei Shima, Hitomi Kashiwagi, Akira Okoshi, Ayako Nakanome, Ryo Funayama, Keiko Nakayama, Takenori Ogawa, Takaaki Abe, Yukio Katori, Kazuhiko Igarashi

This study shows that BACH1 maintains labile iron levels in HNSCC cells, preventing metabolic cell death and enabling proliferation, and that BACH1 inhibition enhances the effect of tipifarnib.

bioRxiv · Apr 7, 2025 · PreprintCancer Biology

TANK binding kinase 1 promotes BACH1 degradation through both phosphorylation-dependent and -independent mechanisms without relying on heme and FBXO22

Liang Liu, Mitsuyo Matsumoto, Miki Watanabe‐Matsui, Tadashi Nakagawa, Yuko Nagasawa, Jingyao Pang, Bert K. K. Callens, Akihiko Muto, Kyoko Ochiai, Hirotaka Takekawa, Mahabub Maraj Alam, Hironari Nishizawa, Mikako Shirouzu, Hiroki Shima, Keiko Nakayama, Kazuhiko Igarashi

International Journal of Molecular Sciences · Apr 9, 2024Peer-reviewedBiochemistry