Author

Hironari Nishizawa

Tohoku UniversityORCID 0000-0001-7024-9942Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Kazuhiko IgarashiiD· 3 shared Akihiko MutoiD· 2 shared Hiroki ShimaiD· 2 shared Keiko NakayamaiD· 2 shared Mitsuyo MatsumotoiD· 2 shared Akari Endo· 1 shared Akira Okoshi· 1 shared Ayako NakanomeiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

Kazuhiko IgarashiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistryGastro Hep AdvancesPeer-reviewedSep 24, 2025

Cysteine restriction induces ferroptosis depending on the polyamine biosynthetic pathway in hepatic cancer cells

Keisuke Tada, K MITSUYAMA, Hironari Nishizawa…·Kazuhiko Igarashi

This study shows that cysteine restriction induces ferroptosis in hepatic cancer cells via the polyamine biosynthetic pathway, but not in normal hepatocytes.

4 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintApr 7, 2025

Metabolic cell death of labile iron deficiency as a vulnerability of head and neck squamous cancer cells evaded by BACH1

Masahiro Rokugo, Kazuki Nakamura, Mitsuyo Matsumoto…·Kazuhiko Igarashi

This study shows that BACH1 maintains labile iron levels in HNSCC cells, preventing metabolic cell death and enabling proliferation, and that BACH1 inhibition enhances the effect of tipifarnib.

DOI 10.1101/2025.04.07.647470

humanbulk RNA-seq

𝕏 PostBluesky

BiochemistryInternational Journal of Molecular SciencesPeer-reviewedApr 9, 2024

TANK binding kinase 1 promotes BACH1 degradation through both phosphorylation-dependent and -independent mechanisms without relying on heme and FBXO22

Liang Liu, Mitsuyo Matsumoto, Miki Watanabe‐Matsui…·Kazuhiko Igarashi

7 citations

humanprotein sequence

𝕏 PostBluesky