Author

Mohammad T. Mazhab‐Jafari

University Health NetworkORCID 0000-0003-0207-5877Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:microscopy & imaging analysis· 3 Assay:cryo-EM· 2 Research Focus:protein folding & dynamics· 2 Research Focus:protein structure prediction· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexander F. A. KeszeiiD· 3 shared S. M. Naimul HasaniD· 2 shared Adwaith B. UdayiD· 1 shared Alex C.H. LiuiD· 1 shared Anisha HarisiD· 1 shared Bradley T. V. DavisiD· 1 shared Brian RaughtiD· 1 shared David Bruton· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

Alexander F. A. KeszeiORCID

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3 papers

Recent·Most cited

Resolving hidden stoichiometries in Bacterial proteasome activator (Bpa)-substrate complexes by cryo-EM and charge detection mass spectrometry

Bradley T. V. Davis, Adwaith B. Uday, Anisha Haris, Alexander F. A. Keszei, Jakub Ujma, David Bruton, Keith Richardson, Mohammad T. Mazhab‐Jafari, Kevin Giles, Natalie Zeytuni, Siavash Vahidi

This study uses cryo-EM and charge detection mass spectrometry to determine the stoichiometry and structure of Bpa-substrate complexes in Mtb, revealing an undecameric apo form and a Bpa12:HspR2 complex.

Journal of the American Chemical Society · Aug 14, 2026Peer-reviewedBiochemistry

Cryo-EM of AKAP350 reveals fibrillar clusters and a potential association with DNA

David L. Dai, Alexander F. A. Keszei, Elena A. KOLOBOVA, Jonathan R. St‐Germain, S. M. Naimul Hasan, Alex C.H. Liu, Xu Zhang, Brian Raught, James R. Goldenring, Mohammad T. Mazhab‐Jafari

This study uses cryo-EM to show AKAP350 forms fibrillar clusters and interacts with DNA and DNA-binding proteins like NFIB and NCL.

Journal of Molecular Biology · Mar 28, 2025Peer-reviewedBiochemistry

Unveiling the Structural Proteome of an Alzheimer's Disease Rat Brain Model

Elnaz Khalili Samani, S. M. Naimul Hasan, Matthew Waas, Alexander F. A. Keszei, Xiaoxiao Xu, Mahtab Heydari, Mary Elizabeth Hill, JoAnne McLaurin, Thomas Kislinger, Mohammad T. Mazhab‐Jafari

This study uses cryo-EM and BaR to analyze protein complexes in an Alzheimer's rat brain model, revealing structural insights relevant to multiple diseases.

Structure · Nov 29, 2024Peer-reviewedBiochemistry