Author
New York University Abu DhabiORCID 0000-0003-0257-6233Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Elena Magnani, Charlene Chen, Filippo Macchi…·Kirsten C. Sadler
This study shows UHRF1 overexpression in zebrafish hepatocytes leads to diverse senescent states with different Tp53 dependencies and responses to senolytic drugs.
Jacopo Biotti, Livio Muccillo, Filippo Macchi…·Ian Marc Bonapace
The paper identifies a UHRF1-EM framework linking DNA methylation, developmental chromatin states, and prognosis in gastric, renal, and adrenal cancers, showing context-dependent prognostic associations.
Elena Magnani, Filippo Macchi, Tijana Randic…·Kirsten C. Sadler
The paper shows that high UHRF1 levels in zebrafish hepatocytes cause epigenetic disordering, leading to stemness, senescence escape, and tumor heterogeneity in hepatocellular carcinomas.
Bhavani P. Madakashira, Elena Magnani, Shashi Ranjan, Kirsten C. Sadler
The paper shows DNA hypomethylation in zebrafish leads to Cdk4/6 activation, ATR-mediated replication stress, and cell cycle arrest, which restricts liver growth.