Author
New York University Abu DhabiORCID 0009-0000-4683-3348Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Elena Magnani, Charlene Chen, Filippo Macchi…·Kirsten C. Sadler
This study shows UHRF1 overexpression in zebrafish hepatocytes leads to diverse senescent states with different Tp53 dependencies and responses to senolytic drugs.
Elena Magnani, Filippo Macchi, Tijana Randic…·Kirsten C. Sadler
The paper shows that high UHRF1 levels in zebrafish hepatocytes cause epigenetic disordering, leading to stemness, senescence escape, and tumor heterogeneity in hepatocellular carcinomas.
Bhavani P. Madakashira, Elena Magnani, Shashi Ranjan, Kirsten C. Sadler
The paper shows DNA hypomethylation in zebrafish leads to Cdk4/6 activation, ATR-mediated replication stress, and cell cycle arrest, which restricts liver growth.