Cornelius Fischer

The paper introduces circVDJ-seq for efficient T cell receptor profiling from single-cell and spatial multi-omics data, revealing distinct immune microenvironments and T cell clonality patterns in various clinical contexts.

This study identifies endocardial sprouting angiogenesis as a key mechanism in coronary vessel formation, revealing distinct molecular profiles that shape coronary arteries and veins.

The paper identifies a disrupted trophoblast transition in preeclampsia, linking placental pathology to maternal syndrome through multi-omics profiling and in vitro analyses.

This paper introduces a nuclei isolation method for plant tissues followed by single-nuclei RNA-seq, enabling transcriptome analysis of various plant species and tissues.

This study benchmarks 13 scRNA-seq protocols to evaluate their effectiveness in characterizing cell types and states for cell atlas projects.