Sascha Sauer

This study shows that oncogene inactivation-induced senescence both limits tumor growth and promotes relapse by creating a pro-recurrence microenvironment.

The paper compares ESC-derived, neonatal, and adult astrocytes to identify functional and transcriptomic differences across age and culture conditions.

This paper introduces a nuclei isolation method for plant tissues followed by single-nuclei RNA-seq, enabling transcriptome analysis of various plant species and tissues.

This study benchmarks 13 scRNA-seq protocols to evaluate their effectiveness in characterizing cell types and states for cell atlas projects.

The paper maps regulatory elements across C. elegans development and ageing, identifying promoters and enhancers and showing their dynamic accessibility linked to developmental processes.

This study identifies de novo mutations and rare variant burdens in SLE candidate genes, supporting their role in disease pathogenesis.

This study shows that resveratrol's protective effects against stress are due to its pro-oxidative properties, which shift the cellular redox environment and enhance resilience to oxidative stress.