Eric Ji Da Wang

AbSLang-search efficiently retrieves structurally similar antibodies from large sequence databases using a contrastive learning model for CDR RMSD prediction.

This paper introduces Pox-AbDab, a database of antibodies against orthopoxviruses, highlighting challenges in cross-species antibody function and identifying gaps in research.

This study uses computational modeling to show that broadly neutralizing antibodies (bnAbs) promote the evolution of diverse autologous antibodies that target multiple HIV spike epitopes, potentially enabling viral control.

This study shows a novel two-step mechanism for inducing broadly neutralizing HIV antibodies in macaques using a modified SHIV, informing vaccine design.

The paper designs mosaic nanoparticles with SARS-like betacoronavirus RBDs to enhance cross-reactive immune responses in mice, finding that mosaic-7COM elicits stronger responses against zoonotic sarbecoviruses and Omicrons.